KMID : 0828520110150040234
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Journal of the Korean Geriatrics Society 2011 Volume.15 No. 4 p.234 ~ p.239
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A Case of Demyelinating Peripheral Neuropathy Associated with Hashimoto¡¯s Thyroiditis
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Park Jung-Hwan
Hong Sang-Mo Lee Chang-Beom Park Yong-Soo Kim Dong-Sun Choi Woong-Hwan Ahn You-Hern
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Abstract
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Peripheral neuropathy is somewhat common in hypothyroidism. But, demyelinating peripheral neuropathy in Hashimoto¡¯s thyroiditis is extremely rare. The pathophysiology of demyelinating peripheral neuropathy associated with Hashimoto¡¯s thyroiditis is unclear and complex and various mechanisms including the cell mediated and antibody mediated responses may be operative. We report a 68-year-old woman who presented with paresthesia and gait disturbance. She was diagnosed with hypothyroidism 7 years prior and has been on thyroid hormone. Serum antithyroglobulin antibody was significantly elevated. Nerve conduction studies revealed sensory-motor demyelinating polyneuropathy with prolonged distal latencies and reduced conduction velocities. She was under the suspicion of the lymphoma of thyroid. Surgery was performed which turned up to be Hashimoto¡¯s thyroiditis. With the impression of rare demyelinating peripheral neuropathy associated with Hashimoto¡¯s ,now()); after other causes were excluded, she was treated with steroid which ameliorated rapidly her neurological symptoms. So we report this case and review literatures.
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KEYWORD
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Hashimoto, Polyradiculoneuropathy, Steroids
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